Lars Juhl Jensen – University of Melbourne Computing and Information Systems Seminar

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ICSB Conference 2014

SBI Australia connects Japanese and Australian research and industry, and facilitates the sharing of scientific technology, resources and expertise.

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In late 2011, EMBL Australia successfully bid to host the 15th International Conference on Systems Biology in Melbourne in 2014.

SBI Australia welcomes interest from undergraduate and postgraduate students, postdoctoral fellows, and research and industry organisations who would like to be part of this exciting new venture.

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When : Tuesday, 12 November 2013 @ 12 noon

Where : Denis Driscoll Theatrette (Room 3.09), Doug McDonell Building, The University of Melbourne

RSVP : Places are limited, so please RSVP to info@sbiaustralia.org

Methodological advances have in recent years given us unprecedented information on the molecular details of living cells. At the same time hospitals are increasingly collecting detailed information on patients in electronic health records. However, it remains an unsolved challenge to bridge the two and systematically link molecular-level data to their phenotypic consequences at the cellular level such as diseases. Networks have proven to be a very useful abstraction for bridging single-gene and systems-level analysis.

Professor Lars Juhl Jensen will describe the STRING database, which scores and integrates evidence from a diverse range of curated databases, raw data repositories, text-mining methods, and computational prediction methods to provide the most comprehensive protein association network possible. He will also introduce a suite of three new web-based resources that use similar techniques, including text mining, to associate the proteins in the STRING network with cellular compartments, tissues, and diseases to enable systems biology studies of diseases, taking into account both interactions and spatial localization of the proteins.

Lars has worked on literature mining, integration of large-scale experimental databases, and analysis of biological interaction networks since 2003. His research was conducted until 2008 at the European Molecular Biology Laboratory (EMBL) and, more recently from 2009, at the Novo Nordisk Foundation Center for Protein Research at the Panum Institute in Copenhagen. He is also a co-founder and scientific advisor of Intomics A/S. Lars’ work on text mining won the first prize in the “Elsevier Grand Challenge: Knowledge Enhancement in the Life Sciences” in 2009, and he was awarded the Lundbeck Foundation Prize for Young Scientists in 2010. Prior to this, he was recognised and awarded the Lundbeck Foundation Talent Prize in 2003 and his work on cell-cycle research was named “Break-through of the Year” in 2006 by the magazine Ingeniøren. He is a co-author of more than 100 scientific publications that have in total received more than 8000 citations.

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